Cypher VRS™ is the First and Only Full-Featured Video-Rate AFM

Finally, researchers can measure nanoscale dynamic processes at video-rate speeds with all the resolution, versatility and ease of use that are hallmarks of an Asylum Research Cypher™ AFM.

  • High resolution video-rate imaging at up to 625 lines per second
  • Exceptional ease of use— even at 10 frames per second
  • Full range of modes and accessories—unlimited capabilities at normal scan speeds

Register for the webinar" Video-Rate AFM Enables New Research Opportunities">

“Many scientists, like myself, have been inspired by early video-rate AFM results, but have been reluctant to invest in a single purpose AFM with a constrained sample configuration and limited range of scan sizes.  What impresses me about the Cypher VRS is that it can achieve high speed without these constraints while maintaining the microscope’s versatility and ease of use, whether for imaging or force spectroscopy.”  — Jim De Yoreo, Chief Scientist at Pacific Northwest National Laboratory

See what other Cypher users are saying >
 

Cypher VRS brochure

Download the brochure for further details

PDF 2.37MB

Specifications

Video-Rate Scanning Performance

Maximum data pixel rate  Up to 500,000 pixels / s

Maximum line scan rate  Up to 625 lines / s

Maximum frame rate  Determined by the image pixel density selected by the user. The table below gives several examples.

 

320 points

512 points

1024 points

40 lines

13.6

8.5

4.2

64 lines

8.7

5.4

2.7

128 lines

4.5

2.8

1.4

256 lines

2.3

1.5

0.7


X&Y range 
10 µm for line scan rates >40 Hz
(closed-loop scanning)

X&Y sensor noise  <60 pm

Z range  >2 µm

Sample size  Up to 15 mm diameter, though for highest speed performance smaller is better. All results shown here were for samples at least 3 mm in diameter.

Sample mounting  Samples are mounted to the sapphire end cap of the Z scanner using adhesive to maximize speed.

DC height noise  <15 pm (<5 pm typical in quiet lab)

AC height noise  <15 pm

Supported modes  Tapping (with phase) or contact mode

Supported options  Liquid perfusion probe holder

 

Cantilever Deflection Sensing

Four modules are available (purchased separately):

Standard Laser Module: Modulated laser diode source with nominal 10×30 µm spot size. Recommended for most imaging applications at normal speeds.

Standard SLD Module: Superluminescent diode (SLD)source with nominal 10×30 µm spot size. Suggested for contact mode at normal speeds and force curves.

Laser Diode Small Spot Module: Modulated laser diode source with nominal 3×9 µm spot size. Required for tapping mode imaging at video rates.

SLD Small Spot Module: Superluminescent diode source with nominal 3×9 µm spot size. Suggested for contact mode imaging at video rates.

Wavelength  850 nm

DC detector noise  <5 pm

AC detector noise  <25 fmHz  above 100 kHz

Detector bandwidth  DC to 7 MHz

Spot positioning and detector adjustment Fully motorized and software controlled. 

 

Normal-Rate Scanning Performance

Maximum data pixel rate  Up to 500,000 pixels/s

Maximum line scan rate  Up to 156 lines / s

X&Y range 
30 µm for line scan rates ≤40 Hz
10 µm for line scan rates >40 Hz
(closed-loop scanning)

X&Y sensor noise  <60 pm

Z range  >5 µm

Z sensor noise  <50 pm

Sample size  Up to 15 mm diameter

Sample mounting  Samples are mounted magnetically.

DC height noise  <15 pm (<5 pm typical in quiet lab)

AC height noise  <15 pm

Supported modes  See the full list inside for the modes that are included standard and those that are available options.

Supported options  See the full list inside.

(Some modes and all environmental control accessories require a quick swap of the fast Z sample stage for a different stage.)

 

Top-view Bright-Field Optics

Resolution  Diffraction limited (<1 µm), NA=0.45

Field of view  690×920 µm

Illumination  Intensity is software controlled. Manual controls for the aperture and field diaphragms. 

 

blueDrive Photothermal Excitation

Included with all Cypher VRS systems.

User-adjustable DC power  Five ranges (0.1 mW, 0.3 mW, 1 mW, 3 mW and 10 mW), appropriate for most conventional and small cantilevers in both air and liquid environments.

Drive frequency  Up to 8 MHz

Safety  Certified FDA/IEC Class 1 (non-hazardous) 405 nm laser diode with fail-safe interlocks.

 

Instrument Isolation

Vibration <10 pm coupling into deflection for 1 mm / s2 floor acceleration when using built-in passive isolation. No further isolation is necessary for typical laboratories.

Acoustic  Included enclosure provides 20 dB isolation.

 

Service and Support

Warranty  Full two-year comprehensive warranty.

Support  No-charge technical support and expert applications support for the lifetime of the AFM.

 

(Noise measurements are quoted as the average deviation measured in a 1 kHz bandwidth over a full 10 seconds.)

 

 

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